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'Infertile' studies on mitochondrial DNA variation in asthenozoospermic Tunisian men

Identificadores del recurso

2405-5808

https://www.ncbi.nlm.nih.gov/pubmed/28955946

http://hdl.handle.net/20.500.11940/9949

10.1016/j.bbrep.2016.08.002

28955946

Procedencia

(RUNA repositorio institucional de la Consellería de Sanidade - Sergas)

Ficha

Título:: 'Infertile' studies on mitochondrial DNA variation in asthenozoospermic Tunisian men
Tema:: Biophysics; Asthenozoospermia; Biochemistry; DNA; astenozoospermia; biofísica; bioquímica; ADN; Mtdna; Haplogroup; Infertilidad
Descrición:: We reviewed five studies undertaken by the same research group on the possible links between mitochondrial DNA (mtDNA) variation and asthenozoospermia, all carried out on Tunisian men. A thorough assessment of these articles reveals that all five studies were carried out on virtually the same cohort of patients, although this information was concealed by the authors. Thus, the results were 'sliced' in order to unjustifiably maximize the number of publications. In addition, a phylogenetic analysis of their data indicates that the reported results are notably incomplete and deficient. Overall, contrary to the original claims, the association of mtDNA variants with asthenozoospermia finds no support on this saga on Tunisian infertile men.; Instituto de Salud Carlos III; F.M-T received funding fromthe GrantISCIII/INT14/00245 (Cofinanciado FEDER)
Idioma:: English
Relación:: ISCIII/INT14/00245; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613696/pdf/main.pdf
Autor/Productor:: Salas, Antonio; Martinón Torres, Federico; Gómez Carballa, Alberto
Dereitos:: Attribution-NonCommercial-NoDerivatives 4.0 Internacional; http://creativecommons.org/licenses/by-nc-nd/4.0/; Los autores; openAccess
Data:: 2017-11-24T13:35:32Z; 2016
Tipo de recurso:: Artigo

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5. <dc:subject>Biophysics</dc:subject>
6. <dc:subject>Asthenozoospermia</dc:subject>
7. <dc:subject>Biochemistry</dc:subject>
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