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'Infertile' studies on mitochondrial DNA variation in asthenozoospermic Tunisian men
Identificadores del recurso
2405-5808
https://www.ncbi.nlm.nih.gov/pubmed/28955946
http://hdl.handle.net/20.500.11940/9949
10.1016/j.bbrep.2016.08.002
28955946
Procedencia
(RUNA repositorio institucional de la Consellería de Sanidade - Sergas)

Ficha

Título:
'Infertile' studies on mitochondrial DNA variation in asthenozoospermic Tunisian men
Tema:
Biophysics
Asthenozoospermia
Biochemistry
DNA
astenozoospermia
biofísica
bioquímica
ADN
Mtdna
Haplogroup
Infertilidad
Descripción:
We reviewed five studies undertaken by the same research group on the possible links between mitochondrial DNA (mtDNA) variation and asthenozoospermia, all carried out on Tunisian men. A thorough assessment of these articles reveals that all five studies were carried out on virtually the same cohort of patients, although this information was concealed by the authors. Thus, the results were 'sliced' in order to unjustifiably maximize the number of publications. In addition, a phylogenetic analysis of their data indicates that the reported results are notably incomplete and deficient. Overall, contrary to the original claims, the association of mtDNA variants with asthenozoospermia finds no support on this saga on Tunisian infertile men.
Instituto de Salud Carlos III
F.M-T received funding fromthe GrantISCIII/INT14/00245 (Cofinanciado FEDER)
Idioma:
English
Relación:
ISCIII/INT14/00245
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613696/pdf/main.pdf
Autor/Productor:
Salas, Antonio
Martinón Torres, Federico
Gómez Carballa, Alberto
Derechos:
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
Los autores
openAccess
Fecha:
2017-11-24T13:35:32Z
2016
Tipo de recurso:
Artigo

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    5. <dc:subject>Biophysics</dc:subject>

    6. <dc:subject>Asthenozoospermia</dc:subject>

    7. <dc:subject>Biochemistry</dc:subject>

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