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Removing exogenous information using pedigree data

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Título:: Removing exogenous information using pedigree data
Tema:: Biología; Agricultura
Descripción:: Management of certain populations requires the preservation of its pure genetic background. When, for different reasons, undesired alleles are introduced, the original genetic conformation must be recovered. The present study tested, through computer simulations, the power of recovery (the ability for removing the foreign information) from genealogical data. Simulated scenarios comprised different numbers of exogenous individuals taking partofthe founder population anddifferent numbers of unmanaged generations before the removal program started. Strategies were based on variables arising from classical pedigree analyses such as founders? contribution and partial coancestry. The ef?ciency of the different strategies was measured as the proportion of native genetic information remaining in the population. Consequences on the inbreeding and coancestry levels of the population were also evaluated. Minimisation of the exogenous founders? contributions was the most powerful method, removing the largest amount of genetic information in just one generation.However, as a side effect, it led to the highest values of inbreeding. Scenarios with a large amount of initial exogenous alleles (i.e. high percentage of non native founders), or many generations of mixing became very dif?cult to recover, pointing out the importance of being careful about introgression events in population
Fuente:: Conservation Genetics, ISSN 1566-0621, 2011-12, Vol. 12, No. 6
Idioma:: English
Relación:: http://oa.upm.es/11795/2/INVE_MEM_2011_107135.pdf; http://www.springerlink.com/content/jn64l4407m03808v/; info:eu-repo/semantics/altIdentifier/doi/10.1007/s10592-011-0255-4
Autor/Productor:: Amador, Carmen; Toro Ibañez, Miguel Angel; Fernandez, Jesus
Editor:: E.T.S.I. Agrónomos (UPM)
Derechos:: http://creativecommons.org/licenses/by-nc-nd/3.0/es/; info:eu-repo/semantics/openAccess
Fecha:: 2011-12
Tipo de recurso:: info:eu-repo/semantics/article; Artículo; PeerReviewed
Formato:: application/pdf

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uketd_dc

Descargar XML

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