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<dc:creator>Ávila-Gandía, Vicente</dc:creator>
<dc:creator>Rubio Arias, Jacobo Ángel</dc:creator>
<dc:creator>Muñoz-Carrillo, Juan Carlos</dc:creator>
<dc:creator>Losada-Zafrilla, Pilar</dc:creator>
<dc:creator>López-Román, Francisco Javier</dc:creator>
<dc:subject>natural spinach extract</dc:subject>
<dc:subject>healthy aging</dc:subject>
<dc:subject>muscle health</dc:subject>
<dc:subject>randomized trial</dc:subject>
<dc:subject>strength training</dc:subject>
<dc:description>The aim of a 12-week randomized double-blind placebo-controlled study was to assess the effect of daily supplementation with a natural extract of Spinacia oleracea L. (4 × 500 mg capsules/day; total 2 g per day) combined with a moderate-intensity training program (1 h session/3 times a week) on skeletal muscle fitness in adults over 50 years of age. Muscle strength assessed by isokinetic and isometric dynamometry improved significantly in the experimental (n = 23) and the placebo (n = 22) groups, but the magnitude of improvement was higher in the experimental group, with between-group differences in almost all variables, including isokinetic at 60° s−1 in knee extension, peak torque (p < 0.007); total work per repetition maximum (p < 0.009); isokinetic at 180°s−1 in knee extension, peak torque (p < 0.002); total work (p < 0.007); total work per repetition maximum (p < 0.005); average power (p < 0.027); isometric in knee extension, peak torque (p < 0.005); and average peak torque (p < 0.002). Similar findings were observed for muscle quality. Changes in quality of life (SF-36) were not found, except for improvements in the role physical (p < 0.023) and role emotional (p < 0.001) domains, likely as a result of the physical training sessions. A nutritional survey did not revealed changes in dietary habits. No adverse events were recorded. In subjects over 50 years of age, moderate-intensity strength training combined with daily supplementation for 12 weeks with a natural extract of Spinacia oleracea L. improved muscle-related variables and muscle quality. Maintaining muscle health is a key component of healthy aging.</dc:description>
<dc:date>2021-12-16T18:37:54Z</dc:date>
<dc:date>2021-12-16T18:37:54Z</dc:date>
<dc:date>2021-12-06</dc:date>
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