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3D Printed Tablets (Printlets) with Braille and Moon Patterns for Visually Impaired Patients

Identificadores del recurso

Awad, A.; Yao, A.; Trenfield, S.J.; Goyanes, A.; Gaisford, S.; Basit, A.W. 3D Printed Tablets (Printlets) with Braille and Moon Patterns for Visually Impaired Patients. Pharmaceutics 2020, 12, 172.

http://hdl.handle.net/10347/21915

10.3390/pharmaceutics12020172

1999-4923

Origin

(Minerva. Repositorio Institucional da Universidade de Santiago de Compostela)

File

Title:: 3D Printed Tablets (Printlets) with Braille and Moon Patterns for Visually Impaired Patients
Tema:: Three-Dimensional Printing; 3D Printed Drug Products; Orally Disintegrating Tablets; Personalised Medicines; Personalized Pharmaceuticals; Blindness; Visual Deprivation; Touch-Reading Compliance; Tactile Patterns; Sight Loss
Description:: Visual impairment and blindness affects 285 million people worldwide, resulting in a high public health burden. This study reports, for the first time, the use of three-dimensional (3D) printing to create orally disintegrating printlets (ODPs) suited for patients with visual impairment. Printlets were designed with Braille and Moon patterns on their surface, enabling patients to identify medications when taken out of their original packaging. Printlets with different shapes were fabricated to offer additional information, such as the medication indication or its dosing regimen. Despite the presence of the patterns, the printlets retained their original mechanical properties and dissolution characteristics, wherein all the printlets disintegrated within ~5 s, avoiding the need for water and facilitating self-administration of medications. Moreover, the readability of the printlets was verified by a blind person. Overall, this novel and practical approach should reduce medication errors and improve medication adherence in patients with visual impairment; The authors thank the Engineering and Physical Sciences Research Council (EPSRC), UK, for their financial support (EP/L01646X); SI
Idioma:: English
Relation:: https://doi.org/10.3390/pharmaceutics12020172
Autor/Productor:: Awad, Atheer; Yao, Aliya; Trenfield, Sarah J.; Goyanes Goyanes, Álvaro; Gaisford, Simon; Basit, Abdul W.
Publisher:: MDPI
Otros colaboradores/productores:: Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica
Rights:: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/); http://creativecommons.org/licenses/by/4.0/; open access
Date:: 2020-04-30T09:12:50Z; 2020
Tipo de recurso:: journal article; VoR

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1. <dc:title>3D Printed Tablets (Printlets) with Braille and Moon Patterns for Visually Impaired Patients</dc:title>
2. <dc:creator>Awad, Atheer</dc:creator>
3. <dc:creator>Yao, Aliya</dc:creator>
4. <dc:creator>Trenfield, Sarah J.</dc:creator>
5. <dc:creator>Goyanes Goyanes, Álvaro</dc:creator>
6. <dc:creator>Gaisford, Simon</dc:creator>
7. <dc:creator>Basit, Abdul W.</dc:creator>
8. <dc:contributor>Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica</dc:contributor>
9. <dc:subject>Three-Dimensional Printing</dc:subject>
10. <dc:subject>3D Printed Drug Products</dc:subject>
11. <dc:subject>Orally Disintegrating Tablets</dc:subject>
12. <dc:subject>Personalised Medicines</dc:subject>
13. <dc:subject>Personalized Pharmaceuticals</dc:subject>
14. <dc:subject>Blindness</dc:subject>
15. <dc:subject>Visual Deprivation</dc:subject>
16. <dc:subject>Touch-Reading Compliance</dc:subject>
17. <dc:subject>Tactile Patterns</dc:subject>
18. <dc:subject>Sight Loss</dc:subject>
19. <dc:description>Visual impairment and blindness affects 285 million people worldwide, resulting in a high public health burden. This study reports, for the first time, the use of three-dimensional (3D) printing to create orally disintegrating printlets (ODPs) suited for patients with visual impairment. Printlets were designed with Braille and Moon patterns on their surface, enabling patients to identify medications when taken out of their original packaging. Printlets with different shapes were fabricated to offer additional information, such as the medication indication or its dosing regimen. Despite the presence of the patterns, the printlets retained their original mechanical properties and dissolution characteristics, wherein all the printlets disintegrated within ~5 s, avoiding the need for water and facilitating self-administration of medications. Moreover, the readability of the printlets was verified by a blind person. Overall, this novel and practical approach should reduce medication errors and improve medication adherence in patients with visual impairment</dc:description>
20. <dc:description>The authors thank the Engineering and Physical Sciences Research Council (EPSRC), UK, for their financial support (EP/L01646X)</dc:description>
21. <dc:description>SI</dc:description>
22. <dc:date>2020-04-30T09:12:50Z</dc:date>
23. <dc:date>2020-04-30T09:12:50Z</dc:date>
24. <dc:date>2020</dc:date>
25. <dc:type>journal article</dc:type>
26. <dc:type>VoR</dc:type>
27. <dc:identifier>Awad, A.; Yao, A.; Trenfield, S.J.; Goyanes, A.; Gaisford, S.; Basit, A.W. 3D Printed Tablets (Printlets) with Braille and Moon Patterns for Visually Impaired Patients. Pharmaceutics 2020, 12, 172.</dc:identifier>
28. <dc:identifier>http://hdl.handle.net/10347/21915</dc:identifier>
29. <dc:identifier>10.3390/pharmaceutics12020172</dc:identifier>
30. <dc:identifier>1999-4923</dc:identifier>
31. <dc:language>eng</dc:language>
32. <dc:relation>https://doi.org/10.3390/pharmaceutics12020172</dc:relation>
33. <dc:rights>© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)</dc:rights>
34. <dc:rights>http://creativecommons.org/licenses/by/4.0/</dc:rights>
35. <dc:rights>open access</dc:rights>
36. <dc:publisher>MDPI</dc:publisher>
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